Recurrent miscarriage (also called recurrent pregnancy loss – RPL) is defined as two or more consecutive miscarriages. Each miscarriage often brings emotional and physical pain. This clinic provides a systematic, compassionate approach to determine and treat the causes.
Understanding whether genetic factors are responsible.
a. Parental Karyotyping
Blood tests of both partners to check for balanced chromosomal translocations or inversions.
These defects can lead to embryo loss but may not affect the parents directly.
b. Product of Conception (POC) Testing
Analysis of the tissue from miscarriage to determine chromosomal abnormalities.
Helps to understand whether loss was due to random genetic issues or a recurring pattern.
Miscarriage can occur due to hormone imbalances critical for a healthy pregnancy.
a. Thyroid Function Tests (T3, T4, TSH)
Hypothyroidism or hyperthyroidism can increase miscarriage risk.
Treated with medications like thyroxine (T4) if needed.
b. Progesterone Deficiency (Luteal Phase Defect)
Progesterone supports early pregnancy.
Low levels may lead to miscarriage. Supplementation via oral, injectable, or vaginal forms is offered.
c. Prolactin and Androgens
High prolactin interferes with ovulation and implantation.
Androgen excess may indicate PCOS, which is linked with pregnancy loss.
d. Diabetes Screening (Fasting Blood Sugar, HbA1c)
Poorly controlled Type 1 or 2 Diabetes increases miscarriage risk.
Preconception sugar control is emphasized.
Structural abnormalities of the uterus can prevent normal embryo development.
a. 2D/3D Pelvic Ultrasound
Detects fibroids, uterine septum, polyps, and adhesions.
b. Hysteroscopy
A minimally invasive procedure that allows direct visualization and treatment of uterine issues.
c. Sonohysterography (Saline Infusion Sonography)
Uses saline in ultrasound for enhanced imaging of the uterus.
d. MRI or CT Scan (for complex cases)
To detect conditions like adenomyosis or double uterus (uterine didelphys).
These conditions cause abnormal clotting, leading to pregnancy loss.
a. Antiphospholipid Antibody Syndrome (APS)
Antibodies attack placental blood vessels causing miscarriage.
Managed with aspirin and heparin.
b. Lupus Anticoagulant Test
Detects abnormal clotting factors linked with systemic lupus erythematosus (SLE).
c. Protein C/S & Factor V Leiden Mutation
Genetic blood clotting disorders screened through blood tests.
Undetected infections may affect the uterus or fetus.
a. TORCH Panel
Tests for Toxoplasmosis, Rubella, CMV, Herpes, and others.
IgM and IgG levels help determine if it’s a past or active infection.
b. Bacterial Vaginosis / Ureaplasma / Listeria Testing
Can be done with vaginal swabs or cultures.
Treated with antibiotics if required.
Your trusted source for women’s healthcare. Our team of experienced physicians provides a comprehensive range of services, from routine checkups to complex surgeries.
